diff --git a/app/brave_main_delegate_browsertest.cc b/app/brave_main_delegate_browsertest.cc
index e119f2fab39..4c9c87b6c06 100644
--- a/app/brave_main_delegate_browsertest.cc
+++ b/app/brave_main_delegate_browsertest.cc
@@ -124,6 +124,9 @@ IN_PROC_BROWSER_TEST_F(BraveMainDelegateBrowserTest, DisabledFeatures) {
     &autofill::features::kAutofillEnableRemadeDownstreamMetrics,
     &autofill::features::test::kAutofillServerCommunication,
     &autofill::features::kAutofillUpstreamAllowAdditionalEmailDomains,
+#if BUILDFLAG(IS_ANDROID)
+    &base::features::kCollectAndroidFrameTimelineMetrics,
+#endif
     &blink::features::kAdAuctionReportingWithMacroApi,
     &blink::features::kAdInterestGroupAPI,
     &blink::features::kAllowURNsInIframes,
@@ -210,6 +213,7 @@ IN_PROC_BROWSER_TEST_F(BraveMainDelegateBrowserTest, DisabledFeatures) {
     &features::kPrivacyGuidePreloadAndroid,
 #endif
     &features::kPrivacySandboxAdsAPIsOverride,
+    &features::kResourceTimingForCancelledNavigationInFrame,
     &features::kSCTAuditing,
     &features::kServiceWorkerAutoPreload,
     &features::kSignedExchangeReportingForDistributors,
@@ -235,6 +239,7 @@ IN_PROC_BROWSER_TEST_F(BraveMainDelegateBrowserTest, DisabledFeatures) {
     &history_clusters::internal::kJourneys,
     &history_clusters::internal::kJourneysImages,
     &history_clusters::internal::kJourneysNamedNewTabGroups,
+    &history_clusters::internal::kJourneysPersistCachesToPrefs,
     &history_clusters::internal::kJourneysZeroStateFiltering,
     &history_clusters::internal::kOmniboxAction,
     &history_clusters::internal::kOmniboxHistoryClusterProvider,
@@ -253,6 +258,7 @@ IN_PROC_BROWSER_TEST_F(BraveMainDelegateBrowserTest, DisabledFeatures) {
     &net::features::kPartitionedCookies,
     &net::features::kThirdPartyPartitionedStorageAllowedByDefault,
     &net::features::kThirdPartyStoragePartitioning,
+    &net::features::kWaitForFirstPartySetsInit,
     &network::features::kFledgePst,
     &network::features::kPrivateStateTokens,
     &network_time::kNetworkTimeServiceQuerying,
@@ -286,10 +292,13 @@ IN_PROC_BROWSER_TEST_F(BraveMainDelegateBrowserTest, DisabledFeatures) {
 #endif
     &permissions::features::kPermissionOnDeviceNotificationPredictions,
     &permissions::features::kPermissionStorageAccessAPI,
-    &privacy_sandbox::kOverridePrivacySandboxSettingsLocalTesting,
     &privacy_sandbox::kEnforcePrivacySandboxAttestations,
+    &privacy_sandbox::kOverridePrivacySandboxSettingsLocalTesting,
+    &privacy_sandbox::kPrivacySandboxFirstPartySetsUI,
+    &privacy_sandbox::kPrivacySandboxProactiveTopicsBlocking,
     &privacy_sandbox::kPrivacySandboxSettings3,
     &privacy_sandbox::kPrivacySandboxSettings4,
+    &privacy_sandbox::kTrackingProtectionOnboardingForceEligibility,
     &promos_features::kIOSPromoPasswordBubble,
     &safe_browsing::kExtensionTelemetry,
     &safe_browsing::kExtensionTelemetryDisableOffstoreExtensions,
diff --git a/chromium_src/base/features.cc b/chromium_src/base/features.cc
new file mode 100644
index 00000000000..83ae39d8594
--- /dev/null
+++ b/chromium_src/base/features.cc
@@ -0,0 +1,18 @@
+/* Copyright (c) 2023 The Brave Authors. All rights reserved.
+ * This Source Code Form is subject to the terms of the Mozilla Public
+ * License, v. 2.0. If a copy of the MPL was not distributed with this file,
+ * You can obtain one at https://mozilla.org/MPL/2.0/. */
+
+#include "src/base/features.cc"
+
+#include "base/feature_override.h"
+
+namespace base::features {
+
+OVERRIDE_FEATURE_DEFAULT_STATES({{
+#if BUILDFLAG(IS_ANDROID)
+    {kCollectAndroidFrameTimelineMetrics, base::FEATURE_DISABLED_BY_DEFAULT},
+#endif
+}});
+
+}  // namespace base::features
diff --git a/chromium_src/components/history_clusters/core/features.cc b/chromium_src/components/history_clusters/core/features.cc
index d8dc01dad85..e84505e01c1 100644
--- a/chromium_src/components/history_clusters/core/features.cc
+++ b/chromium_src/components/history_clusters/core/features.cc
@@ -16,6 +16,7 @@ OVERRIDE_FEATURE_DEFAULT_STATES({{
     {kJourneys, base::FEATURE_DISABLED_BY_DEFAULT},
     {kJourneysImages, base::FEATURE_DISABLED_BY_DEFAULT},
     {kJourneysNamedNewTabGroups, base::FEATURE_DISABLED_BY_DEFAULT},
+    {kJourneysPersistCachesToPrefs, base::FEATURE_DISABLED_BY_DEFAULT},
     {kJourneysZeroStateFiltering, base::FEATURE_DISABLED_BY_DEFAULT},
     {kOmniboxAction, base::FEATURE_DISABLED_BY_DEFAULT},
     {kOmniboxHistoryClusterProvider, base::FEATURE_DISABLED_BY_DEFAULT},
diff --git a/chromium_src/components/privacy_sandbox/privacy_sandbox_features.cc b/chromium_src/components/privacy_sandbox/privacy_sandbox_features.cc
index b2d4fca35a4..5f6c80b8dd2 100644
--- a/chromium_src/components/privacy_sandbox/privacy_sandbox_features.cc
+++ b/chromium_src/components/privacy_sandbox/privacy_sandbox_features.cc
@@ -11,9 +11,13 @@ namespace privacy_sandbox {
 
 OVERRIDE_FEATURE_DEFAULT_STATES({{
     {kEnforcePrivacySandboxAttestations, base::FEATURE_DISABLED_BY_DEFAULT},
+    {kOverridePrivacySandboxSettingsLocalTesting,
+     base::FEATURE_DISABLED_BY_DEFAULT},
+    {kPrivacySandboxFirstPartySetsUI, base::FEATURE_DISABLED_BY_DEFAULT},
+    {kPrivacySandboxProactiveTopicsBlocking, base::FEATURE_DISABLED_BY_DEFAULT},
     {kPrivacySandboxSettings3, base::FEATURE_DISABLED_BY_DEFAULT},
     {kPrivacySandboxSettings4, base::FEATURE_DISABLED_BY_DEFAULT},
-    {kOverridePrivacySandboxSettingsLocalTesting,
+    {kTrackingProtectionOnboardingForceEligibility,
      base::FEATURE_DISABLED_BY_DEFAULT},
 }});
 
diff --git a/chromium_src/content/browser/aggregation_service/aggregation_service_features.cc b/chromium_src/content/browser/aggregation_service/aggregation_service_features.cc
index 88714dd9bbd..d9a1df31df5 100644
--- a/chromium_src/content/browser/aggregation_service/aggregation_service_features.cc
+++ b/chromium_src/content/browser/aggregation_service/aggregation_service_features.cc
@@ -11,6 +11,8 @@ namespace content {
 
 OVERRIDE_FEATURE_DEFAULT_STATES({{
     {kPrivacySandboxAggregationService, base::FEATURE_DISABLED_BY_DEFAULT},
+    {kPrivacySandboxAggregationServiceReportPadding,
+     base::FEATURE_DISABLED_BY_DEFAULT},
 }});
 
 }  // namespace content
diff --git a/chromium_src/content/browser/private_aggregation/private_aggregation_features.cc b/chromium_src/content/browser/private_aggregation/private_aggregation_features.cc
new file mode 100644
index 00000000000..360964af587
--- /dev/null
+++ b/chromium_src/content/browser/private_aggregation/private_aggregation_features.cc
@@ -0,0 +1,17 @@
+/* Copyright (c) 2023 The Brave Authors. All rights reserved.
+ * This Source Code Form is subject to the terms of the Mozilla Public
+ * License, v. 2.0. If a copy of the MPL was not distributed with this file,
+ * You can obtain one at https://mozilla.org/MPL/2.0/. */
+
+#include "src/content/browser/private_aggregation/private_aggregation_features.cc"
+
+#include "base/feature_override.h"
+
+namespace content {
+
+OVERRIDE_FEATURE_DEFAULT_STATES({{
+    {kPrivateAggregationApiBundledEnhancements,
+     base::FEATURE_DISABLED_BY_DEFAULT},
+}});
+
+}  // namespace content
diff --git a/chromium_src/content/common/features.cc b/chromium_src/content/common/features.cc
index 625190bbc33..7dc76db6c00 100644
--- a/chromium_src/content/common/features.cc
+++ b/chromium_src/content/common/features.cc
@@ -11,6 +11,8 @@
 namespace features {
 
 OVERRIDE_FEATURE_DEFAULT_STATES({{
+    {kResourceTimingForCancelledNavigationInFrame,
+     base::FEATURE_DISABLED_BY_DEFAULT},
     {kSignedExchangeReportingForDistributors,
      base::FEATURE_DISABLED_BY_DEFAULT},
     {kServiceWorkerAutoPreload, base::FEATURE_DISABLED_BY_DEFAULT},
diff --git a/chromium_src/net/base/features.cc b/chromium_src/net/base/features.cc
index 2f787d5b478..405e4de921b 100644
--- a/chromium_src/net/base/features.cc
+++ b/chromium_src/net/base/features.cc
@@ -28,6 +28,7 @@ OVERRIDE_FEATURE_DEFAULT_STATES({{
     {kThirdPartyPartitionedStorageAllowedByDefault,
      base::FEATURE_DISABLED_BY_DEFAULT},
     {kThirdPartyStoragePartitioning, base::FEATURE_DISABLED_BY_DEFAULT},
+    {kWaitForFirstPartySetsInit, base::FEATURE_DISABLED_BY_DEFAULT},
 }});
 
 BASE_FEATURE(kBraveEphemeralStorage,