diff --git a/changes/48214-dashboard-hosts-enrolled-keyboard-accessible b/changes/48214-dashboard-hosts-enrolled-keyboard-accessible
new file mode 100644
index 0000000000..0510c2adf1
--- /dev/null
+++ b/changes/48214-dashboard-hosts-enrolled-keyboard-accessible
@@ -0,0 +1 @@
+- Made the per-platform entries in the dashboard "Hosts enrolled" chart keyboard accessible: each platform with hosts is now focusable via Tab, activatable with Enter/Space, has a visible focus indicator, and exposes an accessible name (e.g. "macOS hosts").
diff --git a/frontend/pages/DashboardPage/cards/HostsEnrolledCard/HostsEnrolledCard.tests.tsx b/frontend/pages/DashboardPage/cards/HostsEnrolledCard/HostsEnrolledCard.tests.tsx
index c91c926824..cd3731870d 100644
--- a/frontend/pages/DashboardPage/cards/HostsEnrolledCard/HostsEnrolledCard.tests.tsx
+++ b/frontend/pages/DashboardPage/cards/HostsEnrolledCard/HostsEnrolledCard.tests.tsx
@@ -1,7 +1,8 @@
 /* eslint-disable @typescript-eslint/no-empty-function, class-methods-use-this */
 import React from "react";
-import { render, screen } from "@testing-library/react";
+import { fireEvent, render, screen } from "@testing-library/react";
 import { InjectedRouter } from "react-router";
+import { ILabelSummary } from "interfaces/label";
 
 import HostsEnrolledCard, { formatPercent } from "./HostsEnrolledCard";
 
@@ -43,6 +44,18 @@ class MockResizeObserver {
 
 const noopRouter = ({ push: () => undefined } as unknown) as InjectedRouter;
 
+// Built-in labels keyed to PLATFORM_NAME_TO_LABEL_NAME so the card can resolve a
+// hosts-list link for each platform.
+const builtInLabels: ILabelSummary[] = [
+  { id: 10, name: "macOS", label_type: "builtin" },
+  { id: 11, name: "MS Windows", label_type: "builtin" },
+  { id: 12, name: "All Linux", label_type: "builtin" },
+  { id: 13, name: "chrome", label_type: "builtin" },
+  { id: 14, name: "iOS", label_type: "builtin" },
+  { id: 15, name: "iPadOS", label_type: "builtin" },
+  { id: 16, name: "Android", label_type: "builtin" },
+];
+
 const counts = {
   darwin: 21925,
   windows: 120,
@@ -117,4 +130,72 @@ describe("HostsEnrolledCard", () => {
       expect(screen.getByText(label)).toBeInTheDocument();
     });
   });
+
+  // Regression: the per-platform labels must be keyboard-operable, not just
+  // mouse-clickable SVG text. See #48214.
+  describe("keyboard accessibility", () => {
+    it("exposes platforms with hosts as focusable, accessibly named buttons", () => {
+      render(
+        <HostsEnrolledCard
+          counts={counts}
+          totalHostCount={22070}
+          builtInLabels={builtInLabels}
+          router={noopRouter}
+        />
+      );
+
+      const macButton = screen.getByRole("button", { name: "macOS hosts" });
+      expect(macButton).toBeInTheDocument();
+      // Reachable via Tab (tabindex 0).
+      expect(macButton).toHaveAttribute("tabindex", "0");
+
+      // A platform whose display label ("ChromeOS") differs from its built-in
+      // label name ("chrome") still resolves and becomes operable.
+      expect(
+        screen.getByRole("button", { name: "ChromeOS hosts" })
+      ).toBeInTheDocument();
+    });
+
+    it("does not turn platforms with zero hosts into buttons", () => {
+      render(
+        <HostsEnrolledCard
+          counts={counts}
+          totalHostCount={22070}
+          builtInLabels={builtInLabels}
+          router={noopRouter}
+        />
+      );
+
+      // iOS/iPadOS/Android have a count of 0, so they should stay plain text.
+      expect(
+        screen.queryByRole("button", { name: "iOS hosts" })
+      ).not.toBeInTheDocument();
+    });
+
+    it("navigates to the platform's hosts list on Enter and Space", () => {
+      const push = jest.fn();
+      const router = ({ push } as unknown) as InjectedRouter;
+
+      render(
+        <HostsEnrolledCard
+          counts={counts}
+          totalHostCount={22070}
+          builtInLabels={builtInLabels}
+          currentTeamId={3}
+          router={router}
+        />
+      );
+
+      const macButton = screen.getByRole("button", { name: "macOS hosts" });
+
+      fireEvent.keyDown(macButton, { key: "Enter" });
+      fireEvent.keyDown(macButton, { key: " " });
+
+      expect(push).toHaveBeenCalledTimes(2);
+      // Links to the macOS built-in label (id 10) while preserving the fleet.
+      const expectedPath = expect.stringMatching(/\/labels\/10.*fleet_id=3/);
+      expect(push).toHaveBeenNthCalledWith(1, expectedPath);
+      expect(push).toHaveBeenNthCalledWith(2, expectedPath);
+    });
+  });
 });
diff --git a/frontend/pages/DashboardPage/cards/HostsEnrolledCard/HostsEnrolledCard.tsx b/frontend/pages/DashboardPage/cards/HostsEnrolledCard/HostsEnrolledCard.tsx
index 98dd93d68c..ca9b5d48a5 100644
--- a/frontend/pages/DashboardPage/cards/HostsEnrolledCard/HostsEnrolledCard.tsx
+++ b/frontend/pages/DashboardPage/cards/HostsEnrolledCard/HostsEnrolledCard.tsx
@@ -1,5 +1,6 @@
 import React, { useEffect, useRef, useState } from "react";
 import { InjectedRouter } from "react-router";
+import classnames from "classnames";
 import {
   BarChart,
   Bar,
@@ -119,6 +120,9 @@ interface IYAxisTickProps {
   x?: number;
   y?: number;
   payload?: { value: string; index: number };
+  // recharts merges its own "recharts-cartesian-axis-tick-value" class in via
+  // cloneElement; forward it so recharts' internal tick measurement still works.
+  className?: string;
   fontSize: number;
   isClickable: (index: number) => boolean;
   onLabelClick: (index: number) => void;
@@ -128,17 +132,27 @@ const ClickableYAxisTick = ({
   x = 0,
   y = 0,
   payload,
+  className,
   fontSize,
   isClickable,
   onLabelClick,
 }: IYAxisTickProps): JSX.Element => {
   if (!payload) return <g />;
   const clickable = isClickable(payload.index);
+
+  // Make clickable platform labels real, keyboard-operable controls: focusable
+  // via Tab (tabIndex), announced as buttons, and activatable with Enter/Space
+  // in addition to a mouse click. They navigate programmatically (no href), so
+  // button semantics fit better than a link. See #48214.
+  const handleKeyDown = (event: React.KeyboardEvent<SVGTextElement>) => {
+    if (event.key === "Enter" || event.key === " ") {
+      event.preventDefault();
+      onLabelClick(payload.index);
+    }
+  };
+
   return (
-    <g
-      transform={`translate(${x},${y})`}
-      onClick={clickable ? () => onLabelClick(payload.index) : undefined}
-    >
+    <g transform={`translate(${x},${y})`}>
       <text
         x={0}
         y={0}
@@ -146,7 +160,14 @@ const ClickableYAxisTick = ({
         textAnchor="end"
         fontSize={fontSize}
         fontWeight="normal"
-        className={clickable ? `${baseClass}__tick--clickable` : undefined}
+        className={classnames(className, {
+          [`${baseClass}__tick--clickable`]: clickable,
+        })}
+        role={clickable ? "button" : undefined}
+        tabIndex={clickable ? 0 : undefined}
+        aria-label={clickable ? `${payload.value} hosts` : undefined}
+        onClick={clickable ? () => onLabelClick(payload.index) : undefined}
+        onKeyDown={clickable ? handleKeyDown : undefined}
       >
         {payload.value}
       </text>
diff --git a/frontend/pages/DashboardPage/cards/HostsEnrolledCard/_styles.scss b/frontend/pages/DashboardPage/cards/HostsEnrolledCard/_styles.scss
index 8d0b8eb067..141fc83d17 100644
--- a/frontend/pages/DashboardPage/cards/HostsEnrolledCard/_styles.scss
+++ b/frontend/pages/DashboardPage/cards/HostsEnrolledCard/_styles.scss
@@ -33,6 +33,17 @@
     cursor: pointer;
   }
 
+  // Clickable platform labels are keyboard-operable buttons (see #48214). Give
+  // them a visible focus indicator when reached via keyboard: an outline ring
+  // plus a darker label fill to further set the focused row apart from the
+  // muted inactive ticks. This must be excluded from the recharts outline
+  // suppression below so the ring actually renders.
+  &__tick--clickable:focus-visible {
+    outline: 1px solid $core-focused-outline;
+    outline-offset: 2px;
+    fill: $core-fleet-black;
+  }
+
   &__tooltip {
     background: $core-fleet-black;
     color: $core-fleet-white;
@@ -59,13 +70,15 @@
 
   // Suppress browser focus/click outlines on the chart wrapper, SVG surface,
   // and individual bar rectangles. Recharts wraps each bar in a focusable
-  // <rect> and the chart surface itself is focusable when interactive.
+  // <rect> and the chart surface itself is focusable when interactive. Mouse
+  // focus (`:focus:not(:focus-visible)`) is also suppressed on the clickable
+  // ticks so click-and-hold doesn't flash the browser's default blue ring;
+  // keyboard focus keeps the Fleet ring from the `:focus-visible` rule above.
   .recharts-wrapper,
   .recharts-surface,
   .recharts-bar-rectangle,
   .recharts-rectangle,
-  .recharts-wrapper *:focus,
-  .recharts-wrapper *:focus-visible {
+  .recharts-wrapper *:focus:not(:focus-visible) {
     outline: none !important;
   }
 }