diff --git a/changes/19055-hide-run-script b/changes/19055-hide-run-script
new file mode 100644
index 0000000000..b45a211ea2
--- /dev/null
+++ b/changes/19055-hide-run-script
@@ -0,0 +1 @@
+* Hide the host detail page's "Run script" action from Global and Team Observer/+s.
diff --git a/frontend/pages/hosts/details/HostDetailsPage/HostActionsDropdown/HostActionsDropdown.tests.tsx b/frontend/pages/hosts/details/HostDetailsPage/HostActionsDropdown/HostActionsDropdown.tests.tsx
index 8ec9181d04..51beb650fe 100644
--- a/frontend/pages/hosts/details/HostDetailsPage/HostActionsDropdown/HostActionsDropdown.tests.tsx
+++ b/frontend/pages/hosts/details/HostDetailsPage/HostActionsDropdown/HostActionsDropdown.tests.tsx
@@ -1135,6 +1135,60 @@ describe("Host Actions Dropdown", () => {
 
       await user.click(screen.getByText("Actions"));
 
+      expect(screen.queryByText("Run script")).not.toBeInTheDocument();
+    });
+    it("does not render the Run script action for global observers/+", async () => {
+      // Global observer
+      const render = createCustomRenderer({
+        context: {
+          app: {
+            isGlobalObserver: true,
+            currentUser: createMockUser(),
+          },
+        },
+      });
+      const { user } = render(
+        <HostActionsDropdown
+          hostTeamId={null}
+          onSelect={noop}
+          hostStatus="offline"
+          isConnectedToFleetMdm
+          hostPlatform="windows"
+          hostMdmEnrollmentStatus={null}
+          hostMdmDeviceStatus="unlocked"
+          hostScriptsEnabled
+        />
+      );
+
+      await user.click(screen.getByText("Actions"));
+
+      expect(screen.queryByText("Run script")).not.toBeInTheDocument();
+    });
+    it("does not render the Run script action for team observers/+", async () => {
+      // team observer
+      const render = createCustomRenderer({
+        context: {
+          app: {
+            isTeamObserver: true,
+            currentUser: createMockUser(),
+          },
+        },
+      });
+      const { user } = render(
+        <HostActionsDropdown
+          hostTeamId={1}
+          onSelect={noop}
+          hostStatus="offline"
+          isConnectedToFleetMdm
+          hostPlatform="windows"
+          hostMdmEnrollmentStatus={null}
+          hostMdmDeviceStatus="unlocked"
+          hostScriptsEnabled
+        />
+      );
+
+      await user.click(screen.getByText("Actions"));
+
       expect(screen.queryByText("Run script")).not.toBeInTheDocument();
     });
   });
diff --git a/frontend/pages/hosts/details/HostDetailsPage/HostActionsDropdown/helpers.tsx b/frontend/pages/hosts/details/HostDetailsPage/HostActionsDropdown/helpers.tsx
index 8f35c89a72..3665687d03 100644
--- a/frontend/pages/hosts/details/HostDetailsPage/HostActionsDropdown/helpers.tsx
+++ b/frontend/pages/hosts/details/HostDetailsPage/HostActionsDropdown/helpers.tsx
@@ -226,18 +226,11 @@ const canRunScript = ({
   hostPlatform,
   isGlobalAdmin,
   isGlobalMaintainer,
-  isGlobalObserver,
   isTeamAdmin,
   isTeamMaintainer,
-  isTeamObserver,
 }: IHostActionConfigOptions) => {
   return (
-    (isGlobalAdmin ||
-      isGlobalMaintainer ||
-      isGlobalObserver ||
-      isTeamAdmin ||
-      isTeamMaintainer ||
-      isTeamObserver) &&
+    (isGlobalAdmin || isGlobalMaintainer || isTeamAdmin || isTeamMaintainer) &&
     isScriptSupportedPlatform(hostPlatform)
   );
 };